𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Taking the brake off T cells in chronic viral infection

✍ Scribed by Shin, Eui-Cheol; Rehermann, Barbara

Book ID
109927401
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
380 KB
Volume
12
Category
Article
ISSN
1078-8956

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Cytokine-dependent anti-viral role of CD
Cytokine-dependent anti-viral role of CD4-positive T cells in therapeutic vaccination against chronic hepatitis B viral infection
✍ Fenyu Ren; Keisuke Hino; Yuhki Yamaguchi; Kiyomi Funatsuki; Akio Hayashi; Hiroak πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 210 KB

## Abstract There are several lines of evidence suggesting that specific vaccine therapy with a standard hepatitis B virus (HBV) vaccination reduces HBV replication. The aim of this study was to investigate the anti‐viral mechanism of vaccine therapy in chronic hepatitis B patients. Nineteen patien

Therapeutic vaccination against chronic
Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells
✍ Allan J Zajac; Kaja Murali-Krishna; Joseph N Blattman; Rafi Ahmed πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 740 KB

The goal of therapeutic vaccination is to elicit an antiviral immune response within persistently infected individuals and consequently eradicate the infection. CD8+ T cells are potent mediators of viral clearance; however, during chronic infections CD4+ T cell help is required to sustain antiviral

The role of CD4 and CD8 T cells in viral
The role of CD4 and CD8 T cells in viral infections
✍ Ulrich H Koszinowski; Matthias J Reddehase; Stipan Jonjic πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 772 KB

Presentation of viral antigens to T cells does not require uptake by 'professional' antigen-presenting cells. Viruses have specialized to enter the cells in which they replicate. Virus entry, uncoating and new viral protein synthesis can load both the cytosolic and the endosomal pathway of antigen p