𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4+T cells

✍ Scribed by Kazue Kogina; Hirofumi Shoda; Yumi Yamaguchi; Nelson H. Tsuno; Koki Takahashi; Keishi Fujio; Kazuhiko Yamamoto

Publisher
Korean Society for Molecular and Cellular Biology
Year
2009
Tongue
English
Weight
375 KB
Volume
28
Category
Article
ISSN
1016-8478

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Follicular lymphoma B cells induce the c
Follicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells
✍ Weiyun Z. Ai; Jing-Zhou Hou; Robert Zeiser; Debra Czerwinski; Robert S. Negrin; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 288 KB 👁 1 views

## Abstract There has been accumulating evidence that CD4^+^CD25^+^ FoxP3 expressing regulatory T cells (Treg) are highly concentrated in tumors, thereby fostering an immune‐privileged microenvironment. Some studies have shown that T‐cell receptor (TCR) stimulation can convert conventional T cells

Inhibition of human T cell proliferation
Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells
✍ Claire N. Manzotti; Helen Tipping; Laura C. A. Perry; Karen I. Mead; Patrick J. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB 👁 2 views

CD28 and CTLA-4 are opposing regulators of T cell activation, triggered by the two ligands CD80 and CD86. How these ligands promote either T cell activation via CD28 or inhibition via CTLA-4 is not understood. Using CD80 and CD86 molecules expressed on transfected cells, we have identified a major d

Regulatory CD4+ T cells and the control
Regulatory CD4+ T cells and the control of autoimmune disease
✍ David C Wraith; Kirsty S Nicolson; Nathaniel T Whitley 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 232 KB

The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from autoimmune disease. Recent work has revealed the diver

Differential subcellular localization of
Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4
✍ Seng-Ryong Woo; Nianyu Li; Tullia C. Bruno; Karen Forbes; Scott Brown; Creg Work 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 521 KB

## Abstract CD4 binds to MHC class II molecules and enhances T‐cell activation. The CD4‐related transmembrane protein LAG‐3 (lymphocyte activation gene‐3, CD223) binds to the same ligand but inhibits T‐cell proliferation. We have previously shown that LAG‐3 cell surface expression is tightly regula