## Abstract The relationship between the serum concentrations of tacrine (tetrahydroaminoacridine), two of its metabolites and age, sex and therapeutic effect was examined. The improvement in two measures of cognitive function previously reported to show significant changes with the drug (MMSE and
Tacrine and rate of progression in Alzheimer's disease – relation to ApoE allele genotype
✍ Scribed by M. Sjögren; C. Hesse; H. Basun; G. Köl; H. Thostrup; L. Kilander; J. Marcusson; Å. Edman; A. Wallin; I. Karlsson; M. Troell; G. Wachtmaister; A. Ekdahl; H. Olofsson; A. Sandström; N. Andreasen; L. Minthon; K. Blennow
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 80 KB
- Volume
- 108
- Category
- Article
- ISSN
- 1435-1463
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Thirty‐eight patients with mild to moderate Alzheimer's disease (AD) underwent a neuropsychological test battery and 18‐fluoro‐2‐deoxyglucose (FDG) positron emission tomography (PET) before beginning and at the end of a randomized double‐blind study of an experimental treatment. Twelve
A strong association has been described in cross-sectional studies between the ~4 allele of the apolipoprotein E and late-onset Alzheimer's disease (LOAD). This study addresses the relationship between disease progression and the ~4 allele in 6 2 sporadic LOAD (onset at age 70 and over) patients. Di