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T1307 Comparison of Inflammatory Bowel Disease-Associated and Sporadic Colorectal Cancer: A Nationwide Population-Based Study on Presentation, Treatment and Survival in Ireland

✍ Scribed by Ali, Raja Affendi Raja; Dooley, Cara; Newell, John; Comber, Harry; Egan, Laurence J.


Book ID
123198475
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
44 KB
Volume
138
Category
Article
ISSN
0016-5085

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## Abstract Common single nucleotide polymorphisms (SNPs) in __SMAD7__ (18q21) have been linked to colorectal cancer (CRC) risk in genome‐wide association studies, but little is known about their effects on survival. SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth fa