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Methylation Profiles of Tumor Suppressor Genes in Inflammatory Bowel Disease-Associated and Sporadic Colorectal Cancer: A Comparison

โœ Scribed by Claessen, Marian M. ;Vleggaar, Frank P. ;Schipper, Marguerite E. ;Hinrichs, John W. ;Radersma, Remco D. ;Siersema, Peter D. ;Offerhaus, Johan


Book ID
122331107
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
43 KB
Volume
140
Category
Article
ISSN
0016-5085

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โœ Megan Garrity-Park; Edward V. Loftus Jr; William J. Sandborn; Thomas C. Smyrk ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 627 KB

Background: Patients with extensive, longstanding ulcerative colitis (UC), a disease of chronic colonic inflammation, are at risk for colorectal cancer (CRC). Elucidating the mechanism and fully characterizing the nature of this chronic inflammation offers the potential to identify those at greatest