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T(1;21;8)(p34;q22;q22): a novel variant of t(8;21) in acute myeloblastic leukemia with maturation

✍ Scribed by Abir Gmidène; Rim Frikha; Hlima Sennana; Hatem Elghezal; Moez Elloumi; Ali Saad


Book ID
107577317
Publisher
Springer US
Year
2010
Tongue
English
Weight
252 KB
Volume
28
Category
Article
ISSN
1357-0560

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Homozygosity for 8pter→q22 in acute myel
✍ Dr. Roland Berger 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB

A case of acute nonlymphocytic leukemia with homozygosity for the chromosome segment 8pter-4q22 is reported. A t(8;2 l)(q22;q22) translocation was associated with duplication of the derivative chromosome 8q-and absence of the normal chromosome 8. These rearrangements also yielded hemizygosity for 8q