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T1 and t2 of ferritin at different field strengths: effect on mri

✍ Scribed by Josef Vymazal; Rodney A. Brooks; Olga Zak; Connie Mcrill; Cynthia Shen; Giovanni Di Chiro

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
464 KB
Volume
27
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Nuclear magnetic relaxation times T1 and T2 were measured in ferritin solutions at field strengths from 0.04 to 1.5 T.T1 was relatively constant, but 1/T2 increased linearly with field strength, in agreement with earlier MRI observations in the monkey brain. This finding supports the theory that ferritin is responsible for T2 shortening in brain nuclei containing iron. The linear dependence of 1/T2 on magnetic field is unique and not explained by present theories of the magnetic properties of ferritin.

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