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T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies

✍ Scribed by Camilla A. Lindqvist; Lisa H. Christiansson; Bengt Simonsson; Gunilla Enblad; Ulla Olsson-Strömberg; Angelica S. I. Loskog

Book ID
108782776
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
267 KB
Volume
131
Category
Article
ISSN
0019-2805

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✍ Tetsuro Sasada; Motohide Kimura; Yuka Yoshida; Michiyuki Kanai; Arimichi Takabay 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos