T cells in the infrapatellar fat pad of osteoarthritis patients as a source of IL-6 in the joint
β Scribed by de Jong, A.J.; Kwekkeboom, J.C.; Andersen, S.N.; Kloppenburg, M.; Toes, R.; Ioan-Facsinay, A.
- Book ID
- 122116205
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 118 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1063-4584
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## Abstract ## Objective Obesity is a potent risk factor in knee osteoarthritis (OA). It has been suggested that adipokines, secreted by adipose tissue (AT) and largely found in the synovial fluid of OA patients, derive in part from the infrapatellar fat pad (IFP), also known as Hoffa's fat pad. T
## Abstract Obesity, as a primary risk factor for osteoarthritis (OA), has been shown to alter joint loading, but may also result in metabolic changes characterized by chronic, lowβlevel inflammation due to increased circulating levels of adiposeβderived cytokines, or βadipokines.β The presence of