Microarray Analysis of the Infrapatellar Fat Pad in Knee Osteoarthritis: Relationship with Joint Inflammation
β Scribed by GANDHI, R.; TAKAHASHI, M.; VIRTANEN, C.; SYED, K.; DAVEY, J. R.; MAHOMED, N. N.
- Book ID
- 127325116
- Publisher
- Journal of Rheumatology Publishing Company
- Year
- 2011
- Tongue
- English
- Weight
- 532 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0315-162X
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## Abstract ## Objective Obesity is a potent risk factor in knee osteoarthritis (OA). It has been suggested that adipokines, secreted by adipose tissue (AT) and largely found in the synovial fluid of OA patients, derive in part from the infrapatellar fat pad (IFP), also known as Hoffa's fat pad. T
## Abstract Obesity, as a primary risk factor for osteoarthritis (OA), has been shown to alter joint loading, but may also result in metabolic changes characterized by chronic, lowβlevel inflammation due to increased circulating levels of adiposeβderived cytokines, or βadipokines.β The presence of