𝔖 Bobbio Scriptorium
✦   LIBER   ✦

T cells function via restricted recognition of antigen, not antigen-restricted recognition

✍ Scribed by Rodney E. Langman; Melvin Cohn


Book ID
113133347
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
888 KB
Volume
94
Category
Article
ISSN
0008-8749

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Models for MHC-restricted T-cell antigen
✍ Michael A. Norcross πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 671 KB

Current models for T-cell recognition of foreign antigen depict the T-cell receptor as having a single antibody-like combining site which bindr a complex of MHC and antigen. An alternative hypothesis is presented here; it is proposed that the first domains of the MHC function as inverted V-like regi