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T cells from myasthenic and healthy individuals recognize the acetylcholine receptor: Heterogeneity of antigenic sites on the a-subunit

✍ Scribed by Melms, A.; Malcharek, G.; Sommer, N.; Wiethölter, H.; Schoepfer, R.; Lindstrom, J.


Book ID
122835206
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
85 KB
Volume
4
Category
Article
ISSN
0896-8411

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T cells from normal and myasthenic indiv
✍ Dr A. Melms; G. Malcherek; U. Gern; H. Wiethölter; C. A. Müller; R. Schoepfer; J 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 846 KB

The a-subunit of the nicotinic acetylcholine receptor is the major target of the autoimmune response in myasthenia gravis. We investigated the proliferative response of T cells from patients with myasthenia gravis and healthy volunteers to recombinant polypeptides of the human acetylcholine receptor