CD4+ T-cell subsets and cytokines involv
✍
William O. Weigle; Carole G. Romball
📂
Article
📅
1997
🏛
Elsevier Science
🌐
English
⚖ 464 KB
Peripheral tolerance is induced under conditions that avoid activation of antigen-presenting cells (APCs) to release cytokines. Such tolerance occurs in both CD4+ T helper (Th)-cell subsets (Th1 and Th2), probably because it is induced in precursor cells. By contrast, activation of APCs to release c