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T Cell Replicative Senescence Pleiotropic Effects on Human Aging

โœ Scribed by RITA B. EFFROS


Book ID
111477171
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
105 KB
Volume
1019
Category
Article
ISSN
0890-6564

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EPC-1 (early population doubling level cDNA-1) is a quiescence-specific gene expressed at high levels by early passage WI-38 fibroblasts under conditions of either density-dependent growth arrest or serum deprivation. Late passage WI-38 cells lose the ability to express EPC-1 under all conditions te