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T cell-mediated immune response enhances the severity of myocarditis in secondary cardiotropic virus infection in mice

✍ Scribed by Chiharu Kishimoto; Yuji Hiraoka; Hitoshi Takada


Publisher
Springer
Year
2001
Tongue
English
Weight
157 KB
Volume
96
Category
Article
ISSN
0300-8428

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Immune escape driven by selection pressure from virus-specific CD8 T cells has been demonstrated in both chimpanzees and humans infected with the hepatitis C virus (HCV). Although escape mutations have also been characterized in major histocompatibility complex (MHC) class II-restricted HCV epitopes