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T-Cell-Independent Antiviral B Cell Responses in CD45-Deficient Mice

✍ Scribed by Martin F. Bachmann; Thomas M. Kündig; Daniel E. Speiser; Kim McKall-Faienza; Kenji Kishara; Tak W. Mak; Pamela S. Ohashi

Book ID
112239712
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
99 KB
Volume
175
Category
Article
ISSN
0008-8749

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✍ Eva Szomolanyi-Tsuda; Raymond M Welsh 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 675 KB

Recent work has shown that viruses can act in vivo as T-cell-independent antigens, eliciting protective, isotype-switched antibodies in the absence of conventional TCR alpha beta+ T cell help. Inactivated virus or virus-like particles can stimulate IgM production, but factors induced during live vir