## Abstract Antigen‐specific high zone unresponsiveness to two thymus‐dependent antigens, TNP~560~KLH (2,4,6trinitrophenylkeyhole) limpet hemocyanin and TNP~6~FGG (2,4,6trinitrophenylfowl IgG), was induced __in vitro__. It was found that carrier recognition was required for its production, and
Bacterial superantigens induce T cell unresponsiveness in B cell-deficient mice
✍ Scribed by Thomas Miethke; Claudia Wahl; Klaus Heeg; Hermann Wagner
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 489 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The adapter protein CrkL has been implicated in multiple signal transduction pathways in hematopoietic cells. In T lymphocytes, the recruitment of CrkL‐C3G complexes has been correlated with hyporesponsiveness, implicating CrkL as a potential negative regulator. To test this hypothesis
## Abstract The role(s) of T lymphocytes in the foreign body response has not been thoroughly elucidated. Lymphocytes are known to augment macrophage adhesion and fusion __in vitro__. Furthermore, T lymphocytes are a possible source of the cytokines, IL‐4 and IL‐13, which induce macrophage fusion.
Unit6 d'Immuno-h6matologie et d'Imrnunopathologie., Unit6 de la RageO, H6pital P a s t e d , Paris and Unit6 d'Oncologie Vide\*, Institut Pasteur, Pans The mechanisms of CD4 depletion and hyporesponsiveness during human immunodeficiency virus (HIV) infection are still unknown. Given the ability of