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T-cell depleted bone marrow transplantation for plasma cell myeloma

✍ Scribed by Yehuda, A. Ben ;Or, R. ;Naparstek, E. ;Slavin, S. ;Polliack, A.

Publisher
Springer-Verlag
Year
1988
Weight
330 KB
Volume
56
Category
Article
ISSN
1432-0584

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✦ Synopsis

A 37-year-old male patient with advanced refractory plasma cell myeloma underwent T-cell depleted bone marrow transplantation (BMT) after 7 years of active disease previously treated with combination chemotherapy and irradiation. After the BMT there was marked clinical improvement and the patient is currently in good clinical condition two years after the BMT was performed. However, residual myeloma cells are still seen in the marrow and stable levels of paraprotein are still present in the serum. No GVHD was encountered after BMT. The problems of BMT in myeloma are discussed with a review of the current pertinent literature.

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