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T Cell Apoptosis Causes Peripheral T Cell Depletion in Mice Transgenic for the HIV-1 vpr Gene

✍ Scribed by Jiro Yasuda; Tamaki Miyao; Masakazu Kamata; Yoko Aida; Yoichiro Iwakura


Book ID
112273604
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
947 KB
Volume
285
Category
Article
ISSN
0042-6822

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## Abstract We pursued a breeding strategy intended to generate disease‐resistant mice with exclusive expression of the H‐2^u^‐restricted myelin basic protein (MBP) 1‐11 peptide‐specific transgenic (Tg) T‐cell receptor (TCR) on the T‐cell‐deficient RAG1KO (H‐2^b^) background. Utilizing specific scr