T-cell activation and immunologic synapse
β Scribed by Andrey S. Shaw
- Book ID
- 111639314
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 65 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0257-277X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
An immunological synapse (IS) is formed at the interface between antigen-presenting cells and T cells, and is believed to be the structure responsible for antigen recognition and T-cell activation. However, recent imaging analyses reveal that T-cell receptor microclusters (MCs) formed prior to IS ar
## Abstract ## Objective Leflunomide, a potent diseaseβmodifying antirheumatic drug of the isoxazole class, exhibits antiinflammatory, antiproliferative, and immunosuppressive effects by largely unknown mechanisms, although alterations of pyrimidine synthesis have been proposed. Successful immune