T-2 toxin inhibits mitochondrial function in yeast
โ Scribed by Heather Koshinsky; Sandra Honour; George Khachatourians
- Book ID
- 117057939
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 314 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
The influence of the trichothecene mycotoxin T-2 on the mitochondria of Saccharomyces cerevisiae was studied. T-2 is a cytotoxic molecule inhibiting growth and macromolecular synthesis in S. cerevisiae. At low concentrations, T-2 toxin arrested yeast growth on glycerol medium and at higher concentra
In order to facilitate studies on protein localization to and sorting within yeast mitochondria, we have designed an experimental system that utilizes a new vector and a functional assay. The vector, which we call an LPS plasmid (for leader peptide substitution), employs a yeast COX% gene (the struc