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Statins Synergize With Cyclosporine in Inhibiting Mitochondrial Function in Activated T Cells

โœ Scribed by D.H. Margineantu; D. Hockenbery; P.J. Martin; R. Storb; M. Rotta; M. Mielcarek


Book ID
116282013
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
54 KB
Volume
17
Category
Article
ISSN
1083-8791

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## Abstract We have previously shown that inhibition of the proteolytic activity of the proteasome induces apoptosis and suppresses essential functions of activated human CD4^+^ T cells, and we report now the detailed mechanisms of apoptosis following proteasome inhibition in these cells. Here we s