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Systemic Over-Secretion of Growth Hormone in Transgenic Mice Results in a Specific Pattern of Skeletal Modeling and Adaptation

✍ Scribed by Kuo-Fung Tseng; Steven A. Goldstein


Book ID
111486309
Publisher
American Society for Bone and Mineral Research
Year
1998
Tongue
English
Weight
240 KB
Volume
13
Category
Article
ISSN
0884-0431

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Local expression of human growth hormone
✍ Kuo-Fung Tseng; Jeffrey F. Bonadio; Timothy A. Stewart; Andrew R. Baker; Steven πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 776 KB

## Abstract The effect of local production of human growth hormone on murine cortical bone was investigated using a transgenic mouse model. Femora and humeri from human growth hormone transgenic mice and littermate control mice were obtained, and the geometrical, biomechanical, compositional, and h