There might be rheumatic manifestations of malignant diseases, especially those of the hematological type. Until now, antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in chronic lymphocytic leukemia (CLL) has been reported on only very few occasions. Here, we present our patient with
Systemic mastocytosis in association with chronic lymphocytic leukemia: A rare diagnosis
β Scribed by Patricia Ault; Alice Lynn; Constantine S. Tam; L. Jeffrey Medeiros; Michael J. Keating
- Book ID
- 104040432
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 929 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0145-2126
No coin nor oath required. For personal study only.
β¦ Synopsis
Systemic mastocytosis may be primary or be associated with other hematological malignancies, most commonly myeloid neoplasms. In contrast, the association of systemic mastocytosis with lymphoid neoplasms is comparatively rare, and in the absence of appropriate clinical vigilance the diagnosis may be missed. We report a case of aggressive systemic mastocytosis associated with chronic lymphocytic leukemia (SM-CLL), placing particular emphasis on the investigational algorithm used in establishing this diagnosis, and discussing key clinical considerations in the initiation of therapy.
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