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Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation

✍ Scribed by Jacqueline Blundell; Mehreen Kouser; Craig M. Powell

Book ID: 116791628
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 598 KB
Volume: 90
Category: Article
ISSN: 1074-7427
DOI: 10.1016/j.nlm.2007.12.004

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## Abstract The mammalian target of rapamycin (mTOR) is a downstream effector of the phosphatidylinositol 3‐kinase (PI3K)/Akt (protein kinase B) signaling pathway, which mediates cell survival and proliferation. mTOR regulates essential signal‐transduction pathways, is involved in the coupling of g