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Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks

โœ Scribed by Brent E. Korba; Eric J. Gowans; Frances V. Wells; Bud C. Tennant; Richard Clarke; John L. Gerin


Book ID
116075493
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
921 KB
Volume
165
Category
Article
ISSN
0042-6822

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In vivo transfection of Eastern woodchucks (Marmota monax) with recombinant woodchuck hepatitis virus (WHV) DNA is effective in inducing virus infection for the study of replication, pathogenicity, and oncogenicity of wild-type and mutated WHV. The one drawback to this procedure is the need for prep