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Systemic colchicine inhibits goldfish optic nerve regeneration

โœ Scribed by Roger E. Davis; Barbara E. Schlumpf; Paul D. Klinger


Book ID
113206404
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
605 KB
Volume
73
Category
Article
ISSN
0041-008X

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Antibodies to gangliosides inhibit goldf
โœ J. R. Sparrow; C. McGuinness; M. Schwartz; B. Grafstein ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 662 KB

Intraocular injection of antiserum to mixed ganglioside or to GM1 inhibited the regeneration of goldfish optic axons following an optic nerve crush. For example, injections of antiserum on 5 consecutive days beginning the day before the crush resulted in a decrease of about 40% in the axonal outgrow