Optic nerve regeneration in goldfish under light deprivation
โ Scribed by Leitner, Donald S.; Francis, Andrew; Gazzaniga, M.S.
- Book ID
- 122025321
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 354 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0361-9230
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๐ SIMILAR VOLUMES
Intraocular injection of antiserum to mixed ganglioside or to GM1 inhibited the regeneration of goldfish optic axons following an optic nerve crush. For example, injections of antiserum on 5 consecutive days beginning the day before the crush resulted in a decrease of about 40% in the axonal outgrow
## Abstract Regeneration of the goldfish optic nerve involves massive changes in the structure and pattern of macromolecular synthesis in the retinal ganglion cells. To explore the mechanisms that underlie these events, we investigated the changes in chromatin proteins during the course of regenera