The pathogenic link between POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes, and various other clinical signs) syndrome and Castleman's disease is unclear. Roles for M protein in POEMS syndrome and cytokines in systemic manifestations of multicentric Castleman's disease
Systemic Castleman's disease in association with Evan's syndrome and vitiligo
✍ Scribed by Marsh, Johnathan H. ;Colbourn, Donald S. ;Donovan, Virginia ;Staszewski, Harry
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 443 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0098-1532
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✦ Synopsis
Abstract
Systemic Castleman's disease is a lympho‐proliferative disorder which has been associated with autoimmune phenomena. We report a case of the plasma cell variant of Castleman's disease that was associated with autoimmune hemolytic anemia and autoimmune thrombocytopenia (Evan's syndrome), and vitiligo, the association of which has not been previously reported.
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