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Systemic and local evidence of increasing FAS-mediated apoptosis in inflammatory bowel disease

โœ Scribed by Itou, Hiroaki; Iizuka, Masahiro; Shirasaka, Tomoyuki; Yukawa, Michihiro; Chiba, Mitsuro; Watanabe, Sumio


Book ID
122596509
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
198 KB
Volume
118
Category
Article
ISSN
0016-5085

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## Background: Interleukin-18 (il-18) is increased in the inflamed mucosa of patients with crohn's disease (cd). the balance between this pleiotropic proinflammatory cytokine and its natural inhibitor, il-18-binding protein (il-18bp), may contribute to the pathogenesis of inflammatory bowel disease