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Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis

โœ Scribed by Michihiro Yukawa; Masahiro Iizuka; Yasuo Horie; Kazuo Yoneyama; Tomoyuki Shirasaka; Hiroaki Itou; Masafumi Komatsu; Tsuneo Fukushima; Sumio Watanabe


Book ID
106060638
Publisher
Springer
Year
2001
Tongue
English
Weight
266 KB
Volume
17
Category
Article
ISSN
0179-1958

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## Background: Polyamines are important in cell growth and wound repair, but have also been implicated in inflammation-induced carcinogenesis. polyamine metabolism includes back-conversion of spermine to spermidine by the enzyme spermine oxidase (smo), which produces hydrogen peroxide that causes o