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Systemic and intra-accumbens microinjections of naltrexone interfere with tolerance to ethanol in rats

โœ Scribed by R. K. Varaschin; E. Wazlawik; G. S. Morato


Publisher
Springer
Year
2005
Tongue
English
Weight
275 KB
Volume
182
Category
Article
ISSN
0033-3158

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Tolerance to the hypothermic effect of ethanol (Et-OH) developed in male Wistar rats treated daily with 5g/kg of 20 per cent ET-OH vjv i.g. for 6 days. On Day 6 Et-OH treatment was discontinued and the animals were divided into two groups injected into the nucleus accumbens septi (NAS), either with