𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Systematic synthesis of specifically 13C2H-labeled nucleosides from [ul-13C6]-d-glucose

✍ Scribed by Akira (Mei) Ono; Toko Shiina; Akira Ono; Masatsune Kainosho


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
244 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


A systematic approach, which combines previously reported reactions with appropriate modifications, was established for preparing a variety of selectively deuterated nucleosides from glucoseβ€’ We have developed a systematic method of synthesizing specifically deuterated nucleosides from glucose.


πŸ“œ SIMILAR VOLUMES


A multigram, stereoselective synthesis o
✍ Luigi A. Agrofoglio; Jean-Claude Jacquinet; GΓ©rard Lancelot πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 133 KB

The preparation of t3C-labeled ribonucleosides starting from D-[t3C~]glucose in 45% overall yield is described. The key of this short synthetic way is the dehomologation of di-O-isopropylidene hexofuranose 2 with periodic acid and NaBI-I4 that afforded stereoselectively the labeled ribofuranose deri

Multiply 13C-substituted monosaccharides
✍ Jian Wu; Anthony S. Serianni; Paul B. Bondo πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 682 KB

D-(1,5,6-13C3)Glucose (7) has been synthesized by a six-step chemical method. D-(1,2-13C2)Mannose (1) was converted to methyl D-(1,2-13C2)mannopyranosides (2), and 2 was oxidized with Pt-C and O2 to give methyl D-(1,2-13C2)mannopyranuronides (3). After purification by anion-exchange chromatography,

Synthesis of methionines specifically la
✍ David C. Billington; Bernard T. Golding; Michael J. Kebbell; Ishaq K. Nassereddi πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 478 KB πŸ‘ 1 views

## Abstract Efficient methods for synthesising L‐[methy‐ ^13^C]methionine from [^13^C]iodomethane and L‐methionine, and L‐[3,4‐^13^C~2~] methionine from [^13^C~2~]ethene, are described; the preparation of [3,3‐^2^H~2~]methionine and [2,3,3‐^2^H~3~]methionine from methionine by an exchange method is

13C NMR study of the generation of C2- a
✍ Rudolph Willem; Monique Biesemans; FranΓ§ois Kayser; Professor; Dr. Willy J. Mala πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 918 KB

## Abstract Tumoral pancreatic islet cells of the RIN5mF line were incubated for 120 min in media prepared in ^2^H~2~O and containing D‐[1‐^13^C]glucose, and D‐[2‐^13^C]glucose, and D‐[6‐^13^C]glucose. The generation of C~2~‐ and C~3~‐ deuterated lactic acid was assessed by ^13^C NMR. The interpret

Synthesis of [1,3,5-13C3]benzoic acid an
✍ Kazuki Akira; Shigeo Baba πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 French βš– 417 KB πŸ‘ 1 views

## Abstract The synthesis of [1,3,5‐^13^C~3~]‐ and [2,4,6,7‐^13^C~4~]benzoic acid (5a and 5b) from [2‐^13^C]‐ and [3‐^13^C]sodium pyruvate (1a and 1b), for __in vitro__ and __in vivo__ tracer studies using ^13^C nuclear magnetic resonance (NMR) spectroscopy, is reported. After condensation of 1 to