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Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer

✍ Scribed by Eva Karamitopoulou; Inti Zlobec; Ioannis Panayiotides; Efstratios S. Patsouris; George Peros; George Rallis; Christos Lapas; Petros Karakitsos; Luigi M. Terracciano; Alessandro Lugli


Book ID
116534881
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
910 KB
Volume
42
Category
Article
ISSN
1532-8392

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## Abstract Invasion of colorectal carcinomas (CC) is characterized by nuclear accumulation of β‐catenin, a key component of the Wnt pathway, in scattered tumor cells. β‐catenin acts in cooperation with T‐cell factor (Tcf) HMG‐box transcription factors as a transcriptional activator of genes involv