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System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk

✍ Scribed by Zhi-Qiang Zhao; Qing-Kai Guan; Fei-Yun Yang; Peng Zhao; Bing Zhou; Zhi-Jun Chen

Book ID: 107694040
Publisher: S. Karger AG
Year: 2011
Tongue: English
Weight: 295 KB
Volume: 33
Category: Article
ISSN: 1010-4283
DOI: 10.1007/s13277-011-0287-x

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## Abstract ## BACKGROUND. Lipoxygenases (__LOX__) are major enzymes that metabolize arachidonic acid to hydroxyl‐eicosatetraenoic acids and leukotrienes, which have been implicated in inflammation and colorectal cancer risk. Polymorphisms in __LOX__ genes may influence their function and/or expre