✍ Scribed by Théodor Petrzilka; Kapa K. Prasad; Gérard Schmid
No coin nor oath required. For personal study only.
Condensation of azetidinones 2a and 2b with mercaptan 3 gave respectively compound 10 or a 1:1 mixture of 17 and 17′. Bromination of 10, afforded cis and trans‐bromohydrins 13a and of 17 and 17′ cis and trans‐bromohydrins 18a. Acetylation and reduction with zinc and acetic acid of these bromohydrins gave cephems 4a or 4b and 4b′ respectively.
📜 SIMILAR VOLUMES
**Synthesis of Evernin** Two syntheses of the depside evernin **6** are described. Condensation of methyl acetoacetate and methyl crotonate followed by aromatization and reduction with __Raney__‐Ni led to methyl orsellinate **(3)**. The condensation of everninic acid **(4)**, obtained by partial me
**Synthesis of Eriodermin** The total synthesis of eriodermin (=2,7‐dichloro‐4‐formyl 3‐hydroxy‐8‐methoxy‐1,6‐dimethyl‐11__H__‐dibenzo[__b__,__e__] [1,4]dioxepin‐11‐one) is described.
Telechelic aromatic diamines (1 1) containing an oligo-or polysiloxane chain were prepared in a 4-step synthesis. In the first step 1 -allyloxy-4-nitrobenzene (6) was synthesized and subsequently hydrosilylated with chlorodimethylsilane. In the third step the product (7) was hydrolyzed or condensed
SYNTHESE DE @TRAHYDROTHIfiNOPYRIDINES F. ELOY et A. DERYCKERE Des tetrahydrothienopyridines ont 6th obtenues par formylation reductive des thienopyridines et par reduction par le borohydrure de sodium des sels quaternaires de thienopyridinium. The reductive formylation of thienopyridines and the NaB
Telechelic poly(dimethy1siloxane)s (4, 5, 6) with acetoxy, hydroxyl or 2,3-epoxypropoxy functions as end groups were synthesized. As starting materials chloro-3-acetoxy-[or 3-(2,3epoxypropoxyl-propyldimethylsilanes (2 and 3) were prepared by hydrosilylation of the corresponding allylic derivatives w