Synthetic studies toward verrucarol. 2. Synthesis of the AB ring system
โ Scribed by Kraus, George A.; Roth, Bruce
- Book ID
- 120653166
- Publisher
- American Chemical Society
- Year
- 1980
- Tongue
- English
- Weight
- 862 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
A highly oxygen-functionalized cyclohexenone 2, the AB ring fragment for the aquayamycin synthesis, was efficiently synthesized via stereoselective addition of allylzinc bromide to ketone 3a which, in turn, was available from the optically pure cyclohexane 1,2,3-triol derivative 5.
Synthetic studies toward eletefine, a novel stephaoxocane alkaloid, were undertaken in an attempt to provide a general methodology to aid in the synthesis of other novel stephaoxocanes. An efficient construction of the AB ring system with increased functionality is described which presents a flexibl