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Synthetic studies toward potent cytotoxic agents amphidinolides G and H: Synthesis of the entire C15C26 moiety of the top half

✍ Scribed by T.K. Chakraborty; V.R. Suresh

Book ID
104259987
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
242 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Stereoselective synthesis of the entire (16S, 18S, 21R, 22S, 23R, 25R)-C15-C26 segment 1 of amphidinolides G and H has been achieved for the first time following a highly efficient convergent strategy.

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ChemInform Abstract: Synthetic Studies Toward Potent Cytotoxic Agents Amphidinolides G and H: Synthesis of the Entire C15—C26 Moiety of the Top Half.
✍ T. K. CHAKRABORTY; V. R. SURESH 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Synthetic Studies Toward Potent Cytotoxic Agents Amphidinolides G and H: Synthesis of the Entire C 15 -C 26 Moiety of the Top Half. -The synthesis of segment (IX) utilizes stereoselective allylation of N-acyloxazolidines (I), a diastereoselective aldol condensation between aldehyde (IV) and chiral