✦ LIBER ✦

Synthetic studies on the furan ring of wortmannin

✍ Scribed by Bryan H. Norman; Jonathan Paschal; Chris J. Vlahos

Book ID: 103982949
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 185 KB
Volume: 5
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(95)00191-u

No coin nor oath required. For personal study only.

✦ Synopsis

Synthetic studies on the fungal metabolite, wortmannin, were undertaken in an effort to gain insight into the structure activity relationships of wortmannin analogs on phosphatidylinositol-3'-kinase (PI-3kinase). Our work has focused on the chemistry of the previously unexplored furan ring and has uncovered several interesting and novel chemical transformations, which are described herein.

📜 SIMILAR VOLUMES

Synthetic Studies of Neoclerodane Diterp

Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Selective Modification of the Furan Ring.

✍ Wayne W. Harding; Matthew Schmidt; Kevin Tidgewell; Pavitra Kannan; Kenneth G. H 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Synthetic studies of neoclerodane diterp

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: Selective modification of the furan ring

✍ Wayne W. Harding; Matthew Schmidt; Kevin Tidgewell; Pavitra Kannan; Kenneth G. H 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 136 KB

Synthetic Studies on the HIJK-Ring Fragm

Synthetic Studies on the HIJK-Ring Fragment of Ciguatoxin

✍ Tong-Zhu Liu; Minoru Isobe 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 250 KB

Alternative synthetic approaches to (±)-

Alternative synthetic approaches to (±)-euryfuran via the furan ring transfer reaction

✍ Yoskiyasu Baba; Toshihiro Sakamoto; Seizo Soejima; Ken Kanematsu 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 1010 KB

Abstruct Two effective synthetic approaches to ( f )-euryfuran 1 are described. One synthetic mute makes use. of sequential fumn ring transfer reaction type I and type III as key steps followed by sigmatmpic. rearrangement, and another route proceeded through furan ring transfer reaction type I and

Synthetic studies on breviones: construc

Synthetic studies on breviones: construction of the CDE ring system

✍ Hirosato Takikawa; Manabu Hirooka; Mitsuru Sasaki 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 91 KB

Breviones A-E (1-5), allelopathic agents isolated from Penicillium brevicompactum Dierckx, are structurally unique pentacyclic or hexacyclic diterpenoid derivatives. The synthesis of a structurally simplified model compound (8), corresponding to the characteristic spiro-fused CDE ring portion of 1-4

Synthetic studies on asperparaline A.Syn

Synthetic studies on asperparaline A.Synthesis of the spirosuccinimide ring system

✍ Florenci Gonzalez; Juan F. Sanz-Cervera; Robert M. Williams 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 222 KB

A photooxygenation reaction of 2',2',4',4'-tetramethyl tetrahydroindole (9) followed by a pinacoltype rearrangement furnished 2',2 ',4',4'-tetramethyl-3-spirocydopentylsuccinimide (11). This transformation constitutes a model study for the synthesis of the spirosuccinimide ring system of asperparali