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Synthetic studies on teleocidin IV. An efficient synthesis of (-)-indolactam V

✍ Scribed by Shin-ichi Nakatsuka; Toshiya Masuda; Kunisaku Sakai; Toshio Goto


Book ID
104219391
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
230 KB
Volume
27
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Synthetic studies on teleocidin II. Synt
✍ Shin-ichi Nakatsuka; Toshiya Masuda; Toshio Goto πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 French βš– 240 KB

The same substituent to teleocidin B at 6-and 7-positions of indole nucleus was introduced via intramolecular cyclization and oxidative cleavage of C-N bond at l-position starting from simple indole. Teleocidin B (k) 2) 1s one of the most interesting natural products because of its potent biological

Synthesis of 7-substituted indolactam-V
✍ Yasuyuki Endo; Yasuo Sato; Koichi Shudo πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 641 KB

Indolactam-V, which shares the same partial structure of teleocidins A and B, shows a weak promoting activity compared to teleocidins. It suggests that the hydrophobic moieties substituted on the 6,7positions of teleocidins play a role in increasing the biological activity. 7-Substituted indolacta