Synthetic Studies on Perhydronaphthacenes
β Scribed by Fritz De Pessemier; Paul Vanhee; Dirk Tavernier
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 403 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0037-9646
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## Abstract A practical, highly stereoselective tenβstep synthesis of coenzyme Q~10~ (**1**) has been accomplished (overall yield __ca.__ 28%), starting from commercially available 2,3βdimethoxyβ5βmethylbenzoquinone (__Scheme__). The introduction of the first sideβchain isoprenyl group with (__E__)