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Synthetic Studies on Azacyclotribenzylenes.

✍ Scribed by Kenta Hayashi; Shoko Inoue; Hanae Shimizu; Akiko Kobayashi; Miyuki Ishizaki; Yutaka Matsuoka; Kiyoshi Nishitani; Hiroshi Hara

Publisher
John Wiley and Sons
Year
2005
Weight
24 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract A practical, highly stereoselective ten‐step synthesis of coenzyme Q~10~ (**1**) has been accomplished (overall yield __ca.__ 28%), starting from commercially available 2,3‐dimethoxy‐5‐methylbenzoquinone (__Scheme__). The introduction of the first side‐chain isoprenyl group with (__E__)