Synthetic studies of trichothecenes, an enantioselective synthesis of a C-ring precursor of anguidine
โ Scribed by Dee W. Brooks; Paul G. Grothaus; James T. Palmer
- Book ID
- 104221968
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 254 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A stereoselective construction of the C-ring fragment of trichothecenes from readily available 4-cumyloxy-2-cyclopentenol in 12 steps (24% overall yield) is described. We have recently described an asymmetric synthesis based on the reaction of enones with chiral sulfinylallyl anions.' The utilizatio
A concise synthesis of the oxygen substituted ring A compound 2 found in Taxol w 1a and Taxotere w 1b starting from 2,2dimethylcyclohexane-1,3-dione and proceeding via the key intermediates 8 and 11, is described. The absolute configuration of 2 was established from an X-ray crystal structure determ