Synthetic studies of trans-clerodane diterpenoids and congeners: stereocontrolled total synthesis of (.+-.)-avarol
โ Scribed by Sarma, Aluru S.; Chattopadhyay, Partha
- Book ID
- 120184135
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 741 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
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The first total synthesis of the title compound in racemic form has been accomplished from ketone 4, a readily accessible compound via an intermolecular Diels-Alder approach developed previously for the synthesis of clerodane diterpenoids.
Synthetic Studies on Clerodane Diterpenoids. Part 4. The Total Synthesis of (ยฑ)-6ฮฒ-Acetoxy-2-oxokolavenool. -The title compound (X) belongs to the class of clerodane diterpenoids which possess interesting antifeedant and medicinal properties and are potentially useful as insecticidal, antitumor, an