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Synthetic quinine analogs. I. Synthesis and some chemical transformations of 6'-methoxy-7-oxo-8-rubene

โœ Scribed by Bender, D. R.; Coffen, D. L.


Book ID
126268012
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
848 KB
Volume
33
Category
Article
ISSN
0022-3263

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Regiospecific cyclization of the alcohol &into the bicyclo[ 4.2.21 compound g was achieved via selective activation of the secondary methoxy group and subsequent acid treatment. A side-chain was introduced at the bridge-head position, thus making up the bicyclomycin skeleton. Bicyclomycin, which i