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Synthetic polymer coatings for long-term growth of human embryonic stem cells

✍ Scribed by Villa-Diaz, Luis G; Nandivada, Himabindu; Ding, Jun; Nogueira-de-Souza, Naiara C; Krebsbach, Paul H; O'Shea, K Sue; Lahann, Joerg; Smith, Gary D

Book ID
109900720
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
471 KB
Volume
28
Category
Article
ISSN
1087-0156

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,