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Long-term microcarrier suspension cultures of human embryonic stem cells

✍ Scribed by Steve K.W. Oh; Allen K. Chen; Yanglin Mok; Xiaoli Chen; U-Ming Lim; Angela Chin; Andre B.H. Choo; Shaul Reuveny

Book ID
113894672
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
919 KB
Volume
2
Category
Article
ISSN
1873-5061

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,