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Synthetic Multivalent Ligands as Probes of Signal Transduction

✍ Scribed by Laura L. Kiessling; Jason E. Gestwicki; Laura E. Strong

Book ID: 101988634
Publisher: John Wiley and Sons
Year: 2006
Weight: 8 KB
Volume: 37
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200627272

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Processes such as cell-cell recognition and the initiation of signal transduction often depend on the formation of multiple receptor-ligand complexes at the cell surface. Synthetic multivalent ligands are unique probes of these complex cell-surface-binding events. Multivalent ligands can be used as