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Multivalent RGD synthetic peptides as potent ?V?3 integrin ligands

✍ Scribed by Garanger, Elisabeth; Boturyn, Didier; Coll, Jean-Luc; Favrot, Marie-Christine; Dumy, Pascal


Book ID
119950162
Publisher
Royal Society of Chemistry
Year
2006
Tongue
English
Weight
249 KB
Volume
4
Category
Article
ISSN
1477-0520

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## Abstract Vitronectin receptors Ξ±~v~Ξ²~3~ and Ξ±~v~Ξ²~5~ have emerged as potential therapeutic targets for the treatment of osteoporosis, restenosis, ocular disease, tumor‐induced angiogenesis, metastasis, and sickle‐cell anemia. Among a collection of compounds, a new potent integrin antagonist was