✦ LIBER ✦

Synthetic carbapenem antibiotics III. 1-Methyl thienamycin

✍ Scribed by David H. Shih; Lovji Cama; Burton G. Christensen

Book ID: 104222346
Publisher: Elsevier Science
Year: 1985
Tongue: French
Weight: 275 KB
Volume: 26
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)89154-6

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✦ Synopsis

Total syntheses of 1~ and 18-methyl thienamycin are reported. lb-Methyl thienamycin thebacterial activity of thienamycin and is highly resistant to hydrolysis by DHP-I enzyme.

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